Wing Damian Penaud and lock Romain Taofifenua have tested positive for Covid-19 and will miss France’s Six Nations clash against Wales on Friday.
Penaud is replaced in the starting line-up by Gabin Villiere, who has recovered from injury.
Taofifenua was on the bench when France beat Scotland 11 says ago and two switches among the replacements see call-ups for Mohamed Haouas and Matthis Lebel.
Penaud apart, Les Bleus head coach Fabien Galthie has otherwise retained the team that defeated Scotland.
And that means fears have been allayed about captain and world player of the year Antoine Dupont after he suffered a knock during training on Tuesday.
Victory for France in Cardiff would leave them one win away from guaranteeing a first Six Nations title and Grand Slam since 2010.
— France Rugby (@FranceRugby) March 9, 2022
France team to play Wales
Forwards: 1 Cyril Baille, 2 Julien Marchand, 3 Uini Atonio, 4 Cameron Woki, 5 Paul Willemse, 6 François Cros, 7 Anthony Jelonch, 8 Grégory Alldritt
Backs: 9 Antoine Dupont (Captain), 10 Romain Ntamack, 11 Gabin Villière, 12 Jonathan Danty, 13 Gaël Fickou, 14 Yoram Moefana, 15 Melvyn Jaminet
Replacements: 16 Peato Mauvaka, 17 Jean-Baptiste Gros, 18 Mohamed Haouas, 19 Thibaud Flament, 20 Dylan Cretin, 21 Maxime Lucu, 22 Thomas Ramos, 23 Matthis Lebel